BDBM50134934 5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl-phenol::CHEMBL146826::desethyl isoquine

SMILES CCNCc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1O

InChI Key InChIKey=XWBLHPDICBKAEX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134934   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed