BDBM50135309 6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL128516

SMILES Cc1ccccc1N1C(=O)NCc2nc(Sc3ccc(F)cc3Cl)ccc12

InChI Key InChIKey=NMIPNOFQZFCFCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135309   

TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135309(6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 beta at 1000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135309(6-(2-Chloro-4-fluoro-phenylsulfanyl)-1-o-tolyl-3,4...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed