BDBM50135313 3,5-Dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-3,4-dihydro-2H-pyrido[3,2-d]pyrimidin-1-yl]-benzoic acid methyl ester::CHEMBL129628

SMILES COC(=O)c1cc(Cl)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc23)c(Cl)c1

InChI Key InChIKey=NAAVOCGXGLOQSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135313   

TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135313(3,5-Dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-...)
Affinity DataIC50:  73nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135313(3,5-Dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135313(3,5-Dichloro-4-[6-(4-fluoro-phenylsulfanyl)-2-oxo-...)
Affinity DataIC50: <30nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed