BDBM50135669 3-Piperidin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine::CHEMBL99657

SMILES Nc1nc(N)c2nc(CN3CCCCC3)nnc2n1

InChI Key InChIKey=KHTKOASOSWSGJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135669   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135669(3-Piperidin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135669(3-Piperidin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed