BDBM50135820 2-(pyridin-4-ylamino)ethane-1,1-diyldiphosphonic acid::CHEMBL294191::[1-Phosphono-2-(pyridin-4-ylamino)-ethyl]-phosphonic acid

SMILES OP(O)(=O)C(CNc1ccncc1)P(O)(O)=O

InChI Key InChIKey=PHSBWGJKPMTUGF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135820   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135820(2-(pyridin-4-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135820(2-(pyridin-4-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataIC50:  417nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135820(2-(pyridin-4-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed