BDBM50136824 (4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl)methyl)-25-amino-13-(4-aminobutyl)-7,19,22-tribenzyl-10-((R)-1-hydroxyethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosane-4-carboxylic acid::(S)-25-Amino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,12,15,18-tetra(S)-oxo-9,21-di(R)-oxo-24-oxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid::CHEMBL266477::H-c(Cys3-Phe6-Phe7-DTrp8-Lys9-Thr10-Phe11-Cys14)-OH::ODT-8

SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O

InChI Key InChIKey=PJRZZHKHLDKTKL-AYVMSDBXSA-N

Data  25 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50136824   

TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
The Clayton Foundation Laboratories For Peptide Biology

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst2 receptor by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Binding affinity towards human Somatostatin receptor type 3 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
The Clayton Foundation Laboratories For Peptide Biology

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  41nMAssay Description:Binding affinity towards human Somatostatin receptor type 2 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity towards human Somatostatin receptor type 4 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst3 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst5 receptor in HEK293 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataEC50:  3.33nMAssay Description:Agonist activity at human sst3 receptor expressed in CCL39 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
The Clayton Foundation Laboratories For Peptide Biology

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  41nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst2 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst4 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
The Clayton Foundation Laboratories For Peptide Biology

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  46nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
The Clayton Foundation Laboratories For Peptide Biology

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF-28 from human cloned sst2 receptor expressed in CCL39 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF-28 from human cloned sst3 receptor expressed in CCL39 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF-28 from human cloned sst4 receptor expressed in CCL39 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF-28 from human cloned sst5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst3 receptor by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst4 receptor by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst5 receptor by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136824((4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl...)
Affinity DataIC50:  46nMAssay Description:Binding affinity towards human Somatostatin receptor type 5 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed