BDBM50137744 CHEMBL328740::{(S)-1-[(1S,3aR,6aS)-4,4-Difluoro-1-(1-phenylaminooxalyl-butylcarbamoyl)-hexahydro-cyclopenta[c]pyrrole-2-carbonyl]-2,2-dimethyl-propyl}-carbamic acid isopropyl ester

SMILES CCCC(NC(=O)[C@@H]1[C@H]2CCC(F)(F)[C@H]2CN1C(=O)[C@@H](NC(=O)OC(C)C)C(C)(C)C)C(=O)C(=O)Nc1ccccc1

InChI Key InChIKey=AEXNBJPDMCWYET-ILEFGNDRSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137744   

TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137744(CHEMBL328740 | {(S)-1-[(1S,3aR,6aS)-4,4-Difluoro-1...)
Affinity DataKi:  270nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137744(CHEMBL328740 | {(S)-1-[(1S,3aR,6aS)-4,4-Difluoro-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against Protease using replicon assay in rats at 50 microM concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed