BDBM50139117 CHEMBL3759668

SMILES CN(C)CCCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc(C#N)c(nc12)C#N

InChI Key InChIKey=ZBMBBHHJDDSXOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139117   

TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50139117(CHEMBL3759668)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of purified human topoisomerase 2-mediated relaxation of supercoiled pBR322 DNA at 50 uM incubated for 30 mins in presence of 4 mM ATP by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50139117(CHEMBL3759668)
Affinity DataIC50:  900nMAssay Description:Inhibition of purified human topoisomerase 2-mediated relaxation of supercoiled pBR322 DNA at 50 uM incubated for 30 mins in presence of 1 mM ATP by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed