BDBM50141111 CHEMBL3758901

SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1

InChI Key InChIKey=TWTUJMUGLFWIIG-VQHVLOKHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50141111   

TargetHistone deacetylase 2(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  82nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  28nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  26nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  52nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  52nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50:  123nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed