BDBM50142310 CHEMBL9087::{[4-((E)-2-Benzoyl-2,5-diphenyl-pent-4-enyl)-phenyl]-difluoro-methyl}-phosphonic acid

SMILES OP(O)(=O)C(F)(F)c1ccc(CC(C\C=C\c2ccccc2)(C(=O)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=YXZIPKWVAWBGPL-JLHYYAGUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142310   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142310(CHEMBL9087 | {[4-((E)-2-Benzoyl-2,5-diphenyl-pent-...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142310(CHEMBL9087 | {[4-((E)-2-Benzoyl-2,5-diphenyl-pent-...)
Affinity DataIC50:  5.50E+3nMAssay Description:In vitro inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142310(CHEMBL9087 | {[4-((E)-2-Benzoyl-2,5-diphenyl-pent-...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed