BDBM50142692 CHEMBL3759092
SMILES [H][C@]12Cc3ccc(O)cc3[C@](C)(CCN1CCC(=O)Nc1ccccc1)[C@H]2C
InChI Key InChIKey=VGNUFLUEYYNYCK-POCHDABASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50142692
Affinity DataKi: 0.830nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Displacement of [3H]DAMGO from MOR in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-DPDPE from DOR in rat brain membranes by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]DPDPE from human DOR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]-DPN from rat DOR expressed in EE-HEK293 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [3H]-DPN from rat MOR expressed in EE-HEK293 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-(+)-U69,593 from KOR in guinea pig brain membranes by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]U69593 from rat KOR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:Activity at human KOR expressed in EE-HEK293 cells assessed as pEC50 for effect on (-)U50,488H-induced response (Rvb = 6.2 +/- 0.04 No_unit)More data for this Ligand-Target Pair
TargetKappa-type/Mu-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at MOR/KOR in Dunkin-Hartley guinea pig ileum assessed as inhibition of electrically induced contractions after 5 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+5nMAssay Description:Antagonist activity at DOR in CD1 mouse vas deferens assessed as pEC50 for DPDPE-induced inhibition of EFS-evoked contractions at 1 uM incubated for ...More data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Agonist activity at MOR in Dunkin-Hartley guinea pig ileum assessed as inhibition of EFS-induced contractions incubated for 60 minsMore data for this Ligand-Target Pair