BDBM50142933 CHEMBL3759275

SMILES Cc1c(CCOCCF)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(F)c(F)c1

InChI Key InChIKey=MBXJCQFFWBVPCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142933   

TargetProstaglandin G/H synthase 1(Mus musculus)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142933(CHEMBL3759275)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142933(CHEMBL3759275)
Affinity DataIC50:  29nMAssay Description:Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed