BDBM50143730 (2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL60536

SMILES ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YFXAPTTTXDTWSV-QBPKDAKJSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143730   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143730((2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihyd...)
Affinity DataKi:  21nMAssay Description:Inhibition of human tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143730((2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihyd...)
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143730((2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihyd...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant matrix metalloprotease 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143730((2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihyd...)
Affinity DataKi:  162nMAssay Description:Inhibition of human recombinant matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143730((2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihyd...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of heparin-binding HB-EGF sheddingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed