BDBM50146107 4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(4-methyl-piperazin-1-yl)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide; Dihydrochloride::CHEMBL541309

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(cc(C)nc34)N3CCN(C)CC3)c2Cl)cc1

InChI Key InChIKey=UWHZXDTYTDZLHA-XNTDXEJSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146107   

TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146107(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(4-methyl-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146107(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(4-methyl-...)
Affinity DataIC50:  98nMAssay Description:Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed