BDBM50150518 CHEMBL3769431

SMILES CNc1nc(Nc2ccc(c(OC)c2)-n2cncn2)nc(n1)-c1ccccc1

InChI Key InChIKey=HZFASAKJYOKIIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150518   

TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150518(CHEMBL3769431)
Affinity DataIC50:  180nMAssay Description:Modulation of gamma secretase in human H4 cells transfected with APP751 SWE clone 8.20 mutant assessed as inhibition of amyloid beta (1 to 42) produc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed