BDBM50150518 CHEMBL3769431
SMILES CNc1nc(Nc2ccc(c(OC)c2)-n2cncn2)nc(n1)-c1ccccc1
InChI Key InChIKey=HZFASAKJYOKIIY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50150518
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Modulation of gamma secretase in human H4 cells transfected with APP751 SWE clone 8.20 mutant assessed as inhibition of amyloid beta (1 to 42) produc...More data for this Ligand-Target Pair