BDBM50151341 3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid (3-methoxy-propyl)-amide::CHEMBL177936

SMILES COCCCNS(=O)(=O)c1ccc2CC(CF)NCc2c1

InChI Key InChIKey=DUVDGPSZMWUUNP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151341   

TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50151341(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-s...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of [3H]-methyl-AdoMet binding to human phenylethnolamine N-methyltransferase expressed in E. coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50151341(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-s...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro binding affinity against recombinant human Phenylethanolamine N-methyltransferase expressed in E. coli using [methyl-3H]-AdoMetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50151341(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-s...)
Affinity DataKi:  7.50E+5nMAssay Description:In vitro binding affinity against rat Alpha-2 adrenergic receptor using [3H]-clonidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed