BDBM50151363 4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine::4-(3-chlorophenyl)-5-(1,5-naphthyridin-2-yl)thiazol-2-amine::CHEMBL365663
SMILES Nc1nc(c(s1)-c1ccc2ncccc2n1)-c1cccc(Cl)c1
InChI Key InChIKey=JVXFJMXCRSAZFH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50151363
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.020-0.026)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase(Cryptosporidium parvum (strain Iowa II))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum Iowa II mitogen-activated protein kinaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands(Cryptosporidium parvum (strain Iowa II))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum Iowa II calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF handsMore data for this Ligand-Target Pair
TargetCell division control protein 28, putative(Cryptosporidium parvum (strain Iowa II))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum Iowa II cell division control protein 28More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells pretreated for 30 mins followed by TGFbeta stimulation measured after overnight incubation by...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum Iowa II calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF handsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum calcium-dependent protein kinase 2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF handsMore data for this Ligand-Target Pair