BDBM50152914 1-Ethynyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL363968
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CCC2C(=O)NO)C#C)c2ccccc2n1
InChI Key InChIKey=VACPECYZKUSTIV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50152914
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Effect on TNF-Alpha release in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair