BDBM50153548 3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid (4-diethylamino-cyclohexyl)-amide::CHEMBL428698

SMILES CCN(CC)[C@H]1CC[C@@H](CC1)NC(=O)c1c(C)onc1-c1c(Cl)cccc1Cl

InChI Key InChIKey=YHVDQBFBKGXKDA-SHTZXODSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153548   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153548(3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carbo...)
Affinity DataIC50:  53nMAssay Description:Ability to displace [125I]-ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153548(3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carbo...)
Affinity DataIC50:  57nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed