BDBM50154405 4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2,4-dioxo-butyric acid methyl ester::CHEMBL187971

SMILES CCn1c(cc2cc3OCOc3cc12)C(=O)CC(=O)C(=O)OC

InChI Key InChIKey=TVRSUONJPPSNCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154405   

TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154405(4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2,4-d...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated 3' processing reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50154405(4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2,4-d...)
Affinity DataIC50:  1.54E+7nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154405(4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2,4-d...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed