BDBM50158047 4-(5-Fluoro-3-piperidin-4-yl-indole-1-sulfonyl)-phenylamine::CHEMBL178385

SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C2CCNCC2)c2cc(F)ccc12

InChI Key InChIKey=CMSVYWBZMAWHQM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158047   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158047(4-(5-Fluoro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataKi:  2nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158047(4-(5-Fluoro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed