BDBM50158335 1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid::1-[4-(4-Phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-benzyl]-azetidine-3-carboxylic acid::CHEMBL425563

SMILES OC(=O)C1CN(Cc2ccc(OCc3cc(c(s3)C(F)(F)F)-c3ccccc3)cc2)C1

InChI Key InChIKey=NCUVDYUSQOEZTJ-UHFFFAOYSA-N

Data  11 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50158335   

TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataEC50:  0.5nMAssay Description:Activity at human S1P1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  530nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [33P]S1P binding to S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  23nMAssay Description:Displacement of [33P]S1P from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [33P]S1P from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  530nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50158335(1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)m...)
Affinity DataIC50:  23nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed