BDBM50158445 CHEMBL224781::N-(3-phenylsulfinyl-4-pyridinyl)trifluoromethanesulfonamide

SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1S(=O)c1ccccc1

InChI Key InChIKey=ZQMGNORHKBCQLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158445   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158445(CHEMBL224781 | N-(3-phenylsulfinyl-4-pyridinyl)tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158445(CHEMBL224781 | N-(3-phenylsulfinyl-4-pyridinyl)tri...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed