BDBM50158584 2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-[1,4]naphthoquinone::CHEMBL179743

SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C1=CC(=O)c2ccccc2C1=O

InChI Key InChIKey=WDWPULBPXBZDDC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158584   

TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50158584(2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50158584(2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based mixed inhibition type assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed