BDBM50159906 1-{1-[3-(2-Chloro-5-fluoro-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL182995

SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(F)ccc1Cl

InChI Key InChIKey=IBFJWHIXOKNTCN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159906   

TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159906(1-{1-[3-(2-Chloro-5-fluoro-phenoxy)-4-methyl-penty...)
Affinity DataKi:  56nMAssay Description:Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159906(1-{1-[3-(2-Chloro-5-fluoro-phenoxy)-4-methyl-penty...)
Affinity DataKi:  126nMAssay Description:Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159906(1-{1-[3-(2-Chloro-5-fluoro-phenoxy)-4-methyl-penty...)
Affinity DataIC50:  5.18E+3nMAssay Description:Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed