BDBM50160075 CHEMBL3786230

SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)C(C)(C)C)nc1C

InChI Key InChIKey=PLUYFBRIGUAKBR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50160075   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50160075(CHEMBL3786230)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of histidine-tagged recombinant human full length PI3Kgamma expressed in insect cells preincubated for 15 mins followed by addition of col...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50160075(CHEMBL3786230)
Affinity DataIC50:  720nMAssay Description:Inhibition of histidine-tagged recombinant human full length PI3Kdelta expressed in baculovirus preincubated for 15 mins followed by addition of cold...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50160075(CHEMBL3786230)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of N-terminal histidine6-tagged recombinant human full length PI3Kalpha expressed in baculovirus infected Sf21 insect cells preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50160075(CHEMBL3786230)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length PI3KC2gamma expressed in baculovirus infected Sf21 insect cells preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50160075(CHEMBL3786230)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GST-tagged recombinant human full length VPS34 expressed in baculovirus preincubated for 15 mins followed by addition of cold ATP/gamma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed