BDBM50164959 (4-Bromo-phenyl)-carbamic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester::CHEMBL372419::US8541447, 4
SMILES Brc1ccc(NC(=O)OC2CN3CCC2CC3)cc1
InChI Key InChIKey=SLJMPDGIEKZJAU-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50164959
Affinity DataKi: 40nMAssay Description:Binding assay using alpha 7 nAChR.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibitory constant against [3H]methyllycaconitine binding towards Nicotinic acetylcholine receptor alpha-7 of rat brain hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Binding affinity to alpha7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 167nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2; Not significantMore data for this Ligand-Target Pair