BDBM50167355 CHEMBL189526::{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-[1,3,5]triazin-2-ylamino}-acetic acid

SMILES NS(=O)(=O)c1ccc(CCNc2nc(Cl)nc(NCC(O)=O)n2)cc1

InChI Key InChIKey=YEHQXDOOSDRWKW-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50167355   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  1nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  10.4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5b preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  32nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  32nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  33nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  65nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5a preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  68nMAssay Description:Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  76nMAssay Description:Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167355(CHEMBL189526 | {4-Chloro-6-[2-(4-sulfamoyl-phenyl)...)
Affinity DataKi:  97nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed