BDBM50171829 4-[8-tert-Butyl-3-(3,5-dichloro-phenyl)-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl]-N-(2H-tetrazol-5-yl)-benzamide::CHEMBL425024

SMILES CC(C)(C)C1CCC2(CN(C(=O)N2Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2cc(Cl)cc(Cl)c2)CC1

InChI Key InChIKey=HLAIDTTWJDOFOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171829   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171829(4-[8-tert-Butyl-3-(3,5-dichloro-phenyl)-2-oxo-1,3-...)
Affinity DataIC50:  116nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171829(4-[8-tert-Butyl-3-(3,5-dichloro-phenyl)-2-oxo-1,3-...)
Affinity DataIC50:  36nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed