BDBM50171996 2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-phenoxy)-propoxy]-2,3-dihydro-benzofuran-2-carboxylic acid::CHEMBL192500

SMILES CCCc1cc(SC(F)(F)F)ccc1OCCCOc1ccc2OC(CC)(Cc2c1)C(O)=O

InChI Key InChIKey=JYEWQWZFTYOTGP-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171996   

TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataEC50: <1nMAssay Description:Binding affinity of compound towards Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataEC50:  8nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataEC50:  100nMAssay Description:Effective concentration against hamster PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataIC50:  5.23E+3nMAssay Description:In vitro binding affinity for PPAR-deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration against human PPAR-gamma in Gal4 transactivation assay; 59% response at 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataIC50:  3.11E+3nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed