BDBM50173030 4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-benzamide::CHEMBL197507

SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(cc2)S(N)(=O)=O)c2ccccc12

InChI Key InChIKey=CPOUJZWZCROKKO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173030   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50173030(4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-be...)
Affinity DataKi:  2.59E+4nMAssay Description:Inhibition of recombinant human soluble NPP3 expressed in Sf9 insect cells using ATP as substrate measured after 4 hrs by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50173030(4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-be...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed