BDBM50175407 CHEMBL371484::N-(2,4-difluorobenzyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)quinoline-2-carboxamide

SMILES Fc1ccc(CN(Cc2nncn2Cc2ccc(cc2)C#N)C(=O)c2ccc3ccccc3n2)c(F)c1

InChI Key InChIKey=FBAPTBLKAIFWHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175407   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50175407(CHEMBL371484 | N-(2,4-difluorobenzyl)-N-((4-(4-cya...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against K-Ras farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed