BDBM50175609 5-{3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-pentanoic acid methylamide::BDBM50192305::CHEMBL264587

SMILES CNC(=O)CCCCn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O

InChI Key InChIKey=ASCMVAVLQNEOCG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175609   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50175609(5-{3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50175609(5-{3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6...)
Affinity DataIC50:  560nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50175609(5-{3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6...)
Affinity DataIC50:  560nMAssay Description:Inhibitory concentration required to inhibit recombinant HIV-1 reverse transcriptase More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50175609(5-{3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed