BDBM50178922 7-(4-(aminomethyl)phenyl)-9-cyclopropyl-6-fluoroisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione::CHEMBL383497

SMILES NCc1ccc(cc1)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F

InChI Key InChIKey=JRMYGOQEFDLQJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178922   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178922(7-(4-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178922(7-(4-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed