BDBM50182076 CHEMBL383120::N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-N'-[4-(octahydro-isoquinolin-2-yl)-butyl]-guanidine

SMILES COc1ccc(Br)cc1CCc1c(F)cccc1C(=O)NC(N)=NCCCCN1CCC2CCCCC2C1

InChI Key InChIKey=WJCKGSXDUATLFL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182076   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182076(CHEMBL383120 | N-{2-[2-(5-bromo-2-methoxy-phenyl)-...)
Affinity DataKi:  21nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182076(CHEMBL383120 | N-{2-[2-(5-bromo-2-methoxy-phenyl)-...)
Affinity DataIC50:  390nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed