BDBM50184076 (R,S)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide::CHEMBL380514

SMILES CC(C)N1c2ccccc2C(=NC(NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1

InChI Key InChIKey=BWLUJBRNLJVDMS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184076   

TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50184076((R,S)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50184076((R,S)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)
Affinity DataIC50:  1.81E+3nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed