BDBM50184256 2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL427040

SMILES CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(C)c2)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=AVSJVGZIDNEDSK-UHFFFAOYSA-N

Data  8 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50184256   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataEC50:  303nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataEC50:  1.30E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  26nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  117nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  4.60E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  870nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  871nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  150nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50184256(2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed