BDBM50184262 2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indoline-5-carboxylic acid::CHEMBL207382

SMILES CCCc1c(OCCCN2C(=O)Cc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=JBHHUSIDAMWIJB-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50184262   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184262(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]is...)
Affinity DataIC50:  97nMAssay Description:Inhibition of LXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184262(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]is...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184262(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]is...)
Affinity DataEC50:  4.40E+3nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184262(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]is...)
Affinity DataIC50:  700nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed