BDBM50184272 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-benzo[d][1,2,3]triazol-5-yl)acetic acid::CHEMBL208567

SMILES CCCc1c(OCCCn2nnc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=CQTCWVWUQDCTSG-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184272   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  2.30E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  350nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  410nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  79nMAssay Description:Inhibition of PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184272(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed