BDBM50185148 (+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidine-2-carboxylic acid::CHEMBL207580

SMILES CC(C)Cc1ccc(cc1)-c1nc(no1)-c1ccc(cc1)[C@H]1CC[C@H](N1)C(O)=O

InChI Key InChIKey=XXVGJGHFHPWZAV-UXHICEINSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185148   

TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185148((+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from S1P3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185148((+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiaz...)
Affinity DataIC50:  1.28E+3nMAssay Description:Displacement of [33P]S1P from S1P5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185148((+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiaz...)
Affinity DataIC50:  75nMAssay Description:Displacement of [33P]S1P from S1P1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185148((+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiaz...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [33P]S1P from S1P4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185148((+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [33P]S1P from S1P2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed