BDBM50186723 CHEMBL377123::benzyl (2S,3S)-1-((R)-3-(benzylsulfonyl)-1-((S)-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxopentan-2-ylcarbamate

SMILES CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CS(=O)(=O)Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C=CS(C)(=O)=O

InChI Key InChIKey=SKRPUDBVEVKBAT-SJDWCGKGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186723   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186723(CHEMBL377123 | benzyl (2S,3S)-1-((R)-3-(benzylsulf...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186723(CHEMBL377123 | benzyl (2S,3S)-1-((R)-3-(benzylsulf...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186723(CHEMBL377123 | benzyl (2S,3S)-1-((R)-3-(benzylsulf...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed