BDBM50186827 2-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(4-pyrimidin-5-yl-phenyl)-methyl]-5-fluoro-6-trifluoromethyl-1H-benzoimidazole::CHEMBL379802

SMILES Fc1cc2[nH]c(nc2cc1C(F)(F)F)C(=C1CCN(CC2CC2)CC1)c1ccc(cc1)-c1cncnc1

InChI Key InChIKey=XKXIPIIMLKOLPF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186827   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186827(2-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(4-py...)
Affinity DataKi:  95nMAssay Description:Binding affinity to human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186827(2-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(4-py...)
Affinity DataIC50:  95nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed