BDBM50187638 CHEMBL209185::N,N-bis(4-cyanobenzoyl)-1,3-diphenyl-5-amino-1H-pyrazole

SMILES O=C(N(C(=O)c1ccc(cc1)C#N)c1cc(nn1-c1ccccc1)-c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=QYQLQRQCKPHTKU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187638   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187638(CHEMBL209185 | N,N-bis(4-cyanobenzoyl)-1,3-dipheny...)
Affinity DataKi:  3.05E+3nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187638(CHEMBL209185 | N,N-bis(4-cyanobenzoyl)-1,3-dipheny...)
Affinity DataEC50:  340nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed