BDBM50187691 CHEMBL3828178::US9951026, 1-1

SMILES OC(=O)c1ccc(cc1)C(=C\c1nn(Cc2ccc(F)cc2)c2cc(Cl)ccc12)\C#N

InChI Key InChIKey=LYFOIVOURXRPDK-WOJGMQOQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187691   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM50187691(CHEMBL3828178 | US9951026, 1-1)
Affinity DataIC50: <500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM50187691(CHEMBL3828178 | US9951026, 1-1)
Affinity DataIC50: <500nMAssay Description:Inhibition of recombinant ATX in human Hep3B cells using lysophosphatidylcholine as substrate preincubated for 15 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed