BDBM50190004 (4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methylpyrrolidin-2-one::CHEMBL213311

SMILES CN1[C@@H]([C@H](O)c2ccc(s2)-c2ccc(F)cc2)[C@H](CC1=O)c1ccccc1F

InChI Key InChIKey=KGHQISWDCXQGHL-NPFVIJTESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190004   

Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50:  60nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed