BDBM50191741 CHEMBL215482::N-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethyl)pyridin-2-yl)nicotinamide

SMILES FC(F)(F)c1ccc(NC(=O)c2ccc(nc2)-c2ncccc2C(F)(F)F)cc1

InChI Key InChIKey=OUSGJEOKSJZETD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191741   

TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50191741(CHEMBL215482 | N-(4-(trifluoromethyl)phenyl)-6-(3-...)
Affinity DataIC50:  56nMAssay Description:Antagonist activity against low pH(5.0-5.5)-activated rat VR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50191741(CHEMBL215482 | N-(4-(trifluoromethyl)phenyl)-6-(3-...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity against capsaicin-activated human VR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed