BDBM50193046 CHEMBL3969626

SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)\C=C\c1ccc(O)c(O)c1

InChI Key InChIKey=XITPERBRJNUFSB-SOFGYWHQSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193046   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataKi:  5.30E+3nMAssay Description:Competitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent peptide substrate in presence of NAD+ by Lineweaver-Burk p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataKi:  9.80E+3nMAssay Description:Noncompetitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by Lineweaver-Burk plot a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant human SIRT1 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human SIRT2 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed