BDBM50193124 CHEMBL318663
SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(Cc2ccccc2)cc1
InChI Key InChIKey=PCCSQWIIQMYKAL-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50193124
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Szeged
Curated by ChEMBL
University Of Szeged
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of Wistar rat testicular C17,20-lyase assessed as androst-4-ene-3,17-dione formation using [3H]17-hydroxyprogesterone as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as reduction in 4-OH-midazolam formation by LC/MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in nifedipine oxidation incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of CYP3A4 in pooled human hepatic microsomes using testosterone substrate in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as reduction in 1-OH-midazolam formation by LC/MS/MS analysisMore data for this Ligand-Target Pair