BDBM50194714 CHEMBL3910866

SMILES Fc1cccc(F)c1C1CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1

InChI Key InChIKey=FGGGMFHQRRVFJH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194714   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50194714(CHEMBL3910866)
Affinity DataEC50:  9.70nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed