BDBM50195005 6-(3-cyanobenzylamino)-4-(3-chloro-4-fluorophenylamino)quinoline-3-carbonitrile::CHEMBL221274

SMILES Fc1ccc(Nc2c(cnc3ccc(NCc4cccc(c4)C#N)cc23)C#N)cc1Cl

InChI Key InChIKey=HZNSZIVKTHVWQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195005   

TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50195005(6-(3-cyanobenzylamino)-4-(3-chloro-4-fluorophenyla...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Tpl2 kinase by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed